If the 12V battery is in good condition, then it will easily last four weeks. It will shut off Smart Start/Smart entry after two weeks, but many people like to manually turn it off using the button to the right of the steering column on the lower part of the dash.
If you are not sure about the condition of your 12V battery, particularly if you have ever had to jump start the Prius, then you can get a Batteryminder
http://www.batteryminders.com/batter...--p-16151.html
The Batteryminder will maintain the charge indefinately. Attach it to the jumper terminals.